A new strategy for online adaptive prostate radiotherapy based on cone-beam CT.

TitleA new strategy for online adaptive prostate radiotherapy based on cone-beam CT.
Publication TypeJournal Article
Year of Publication2009
AuthorsBoggula, R, Lorenz, F, Abo-Madyan, Y, Lohr, F, Wolff, D, Boda-Heggemann, J, Hesser, J, Wenz, F, Wertz, H
JournalZeitschrift für medizinische Physik
Date Publishedjan
KeywordsComputer-Assisted, Computer-Assisted: methods, Humans, Imaging, Male, Online Systems, Patient Positioning, Phantoms, Prostate, Prostate: anatomy & histology, Prostate: radiography, Prostatic Neoplasms, Prostatic Neoplasms: radiography, Prostatic Neoplasms: radiotherapy, Radiotherapy Dosage, Radiotherapy Planning, Rectum, Rectum: anatomy & histology, Rectum: radiography, Tomography, X-Ray Computed, X-Ray Computed: methods

Interfractional organ motion and patient positioning errors during prostate radiotherapy can have deleterious clinical consequences. It has become clinical practice to re-position the patient with image-guided translational position correction before each treatment to compensate for those errors. However, tilt errors can only be corrected with table corrections in six degrees of freedom or "full" adaptive treatment planning strategies. Organ shape deformations can only be corrected by "full" plan adaptation. This study evaluates the potential of instant treatment plan adaptation (fast isodose line adaptation with real-time dose manipulating tools) based on cone-beam CT (CBCT) to further improve treatment quality.

Citation Key Boggula2009
PubMed ID19962084